Prevalence of Urinary Tract Infection among Suspected Female Patients Attending Manipal Teaching Hospital, Pokhara, Nepal

Abstract

Urinary tract infection (UTI) is a serious health problem affecting millions of people, commonly females, each year around the world. UTI is defined by a combination of clinical features or symptoms and the presence of bacteria in urine or presence of more than 100,000 CFU/mL after urine culture. Clinical symptoms of UTI include frequency, dysuria, abdominal pain, back pain, fever, and urgency. Diagnosis of UTI relies on both urinalysis and urine culture. This cross-sectional study was conducted to determine the prevalence of urinary tract infections (UTIs), their common bacterial etiology of community, hospital-acquired UTI and their antibiotic sensitivity pattern of females age ranging from18 to 30 years visiting Manipal Teaching Hospital (MTH). This study was conducted in the period between 20th June and 20th September, including 300 suspected female patients. The most common pathogens causing UTI are Escherichia coli (61.25%), Enterococcus species (6.25%), Klebsiella pneumoniae (5%), CONS (5%), Acinitobacter species (3.75%), Citrobacter species (3.75%) and Staphylococcus aureus (2.50%). UTI must be recognized and treated rapidly with an appropriate antibiotic to minimize any morbidity, mortality, and renal damage from acute UTI. The antibiotic sensitivity patterns of most commonly used drugs were found to be Nitrofurantoin 19 (90.47%), Gentamycin 52 (82.53%), Norfloxacin 47 (82.45%), Amikacin 16 (80%), Ciprofloxacin 10 (76.92%), Ofloxacin 4 (40%), Nalidixic acid 39 (62.9%), Cotrimoxazole 33 (55.93%), Cefazolin 12 (38.7%), Cephalexin 6 (37.5%), Penicillin 1 (12.5%) and Ampicillin 4 (7.40%) sensitive.

Keywords: Urinary tract infection, pyuria, urinalysis, antibiotic sensitivity patterns