Comparative Aphrodisiac Activity of Formulated Tablet of Bombax Ceiba Linn. Extract with Sildenafil Citrate Tablet in Male Mice

Abstract

The present work deals with pharmacological studies of formulated tablet of Bombax ceiba Linn root extract comparing with marketed one. An aphrodisiac activity by mating behavior test model was investigated. The dissolved tablet slurry (400 mg/kg body wt./day) was administered orally by gavages for 28 days. Mount latency (ML), intromission latency (IL), ejaculation latency (EL), mounting frequency (MF), intromission frequency (IF), ejaculation frequency (EF) and post-ejaculatory interval (PEI) are the parameters observed before and during the sexual behavior study at day 0, 7, 14, 21, and 28. The formulated tablet reduced significantly ML, IL, EL and PEI (p<0.05). The formulated tablet also increased significantly MF, IF and EF (p<0.05) as compared to the marketed formulation (Sildenafil Citrate-100 gm). These effects were observed in sexually active and inactive male mice. Bombax ceiba roots extract tablet (400 mg/kg body wt.) has comparative aphrodisiac activity with that of marketed formulation (Sildenafil citrate-100 mg) in inactive mice.

Keywords: Bombax ceiba, aphrodisiac, formulated tablet, sexual behavior study

Cite this Article

Pallavi D Rai, Sharada L Deore, Irfan A Farooqui et al. Comparative aphrodisiac activity of formulated tablet of bombax ceiba linn. extract with sildenafil citrate tablet in male mice. Research & Reviews: Journal of Pharmacology. 2015; 5(3): 19–26p.