Spectral, thermal, electrochemical and biological studies of Co(II), Ni(II), Cu(II) and Zn(II) complexes derived from 4-(3-bromo-4-hydroxy-5-methoxybenzylideneamino)-3-mercapto-6-methyl-5-oxo-1,2,4-triazine.
Klíčová slova:
Synthesis, 1, 2, 4-triazine, Schiff base, Antimicrobial activity, Metal complexes.Abstrakt
The Schiff base4-(3-bromo-4-hydroxy-5-methoxybenzylideneamino)-3-mercapto-6-methyl-5-oxo-1,2,4-triazine and its Co(II), Ni(II), Cu(II) and Zn(II) complexes have been synthesized and characterized by IR, NMR, electronic, ESR, fluorescence, thermal, magnetic moment and electrochemical studies. IR and thermal data support the presence of coordinated water in the metal complexes. The electronic spectral and magnetic moment measurements indicate octahedral geometry for Co(II), Ni(II) and Zn(II) complexes and square planar for Cu(II) complexes. Biological studies of the ligand and its metal complexes have been carried out in vitro against Gram-positive (Staphylococcus aureus, Bacillus subtilis), Gram-negative (Escherichia coli) bacteria and fungi (Aspergillus niger, Aspergillus flavus). The results show increased antibacterial and antifungal activity of the metal complexes as compared to the ligand.Keywords: Synthesis, 1,2,4-triazine, Schiff base, antimicrobial activity, metal complexes
Publikováno
Číslo
Sekce
Licence
Declaration and Copyright Transfer Form
(to be completed by authors)
I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.
· I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
· I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
· I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
· I/We also agree to the authorship of the article in the following order:
Author’s name
1. ________________
2. ________________
3. ________________
4. _______________
We Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal. |
