Hydrotropes as Effective Reaction Media for the Synthesis of Carbamazepine

Autores/as

  • Jagannath J. Kadam
  • Ajay Patil
  • Vijay G. Bhawe
  • Manohar V. Lokhande DEPARTMENT OF CHEMISTRY SATHAYE COLLEGE, VILE PARLE EAST MUMBAI-400057 INDIA

Palabras clave:

Hydrotropes, xylene sulfonic acid (XSA), cumene sulfonic acid (CSA), (n-BBSA), n-Butyl benzene sulfonic acid (n-BBSA), isobutyl benzene sulfonic acid (I-BBSA), 1HNMR, IR.

Resumen

 The paper describes the synthesis of Carbamazepine. It is used as an anticonvulsant and antiemetic agent. It is also used in the treatment of pain associated with trigeminal neuralgia, often within 24 to 48 hr. The synthesis of Carbamazepine was carried out using four different hydrotropes. The effects of hydrotropes on yield, rate constant and activation energy at various temperatures and concentrations were studied.Keywords: Hydrotropes, xylene sulfonic acid (XSA), cumene sulfonic acid (CSA), (n-BBSA): n-Butyl benzene sulfonic acid (n-BBSA), isobutyl benzene sulfonic acid (I-BBSA), 1HNMR, IR.

Biografía del autor/a

  • Manohar V. Lokhande, DEPARTMENT OF CHEMISTRY SATHAYE COLLEGE, VILE PARLE EAST MUMBAI-400057 INDIA
    ASSIATANT PROFESSOR IN CHEMSITRY

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Publicado

2012-08-16

Número

Vol. 3 Núm. 2 (2012)

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