Antibacterial and Antifungal Activities of Mirabilis jalapa of Indian Origin

Autor/innen

  • chikku thayamma k m University of Mysore image/svg+xml
  • Dr. Savitha Gujjaiah Department of Chemistry, Maharani’s Science College for Women, Mysore

Schlagwörter:

Mirabilis jalapa L., antimicrobial activity, agar diffusion, broth dilution, phytochemical screening

Abstract

The in vitro antimicrobial activity of Mirabilis jalapa leaf extract was studied against selected pathogenic and non-pathogenic microorganisms Escherichia coli, Bacillus subtilis, Klebsiella pneumoniae, Penicillium chrysogenum, Auriparus flaviceps and Trichoderma viridae by using agar diffusion and broth dilution methods. Leaves were extracted using solvents petroleum ether, chloroform and methanol. Among the solvents tested, petroleum ether and chloroform extracts showed good antimicrobial activity against the selected pathogens. The growth inhibitors were calculated with reference to the control which contains only microbial sample in broth without any inhibitors (100% growth). Further, the qualitative phytochemical screening of leaf extract of the plant reveals the presence of tannins, saponins, alkaloids and flavonoids which may be responsible for its antimicrobial properties. The results justify the ethanomedical use of the plant in different countries for treatment of bacterial infections, fungal infections and inflammations. The antibacterial and antifungal activities of Mirabilis jalapa of Indian origin is discussed in the present paper.

Autor/innen-Biografie

  • chikku thayamma k m, University of Mysore
    Department of biotechnology

Downloads

Zusätzliche Dateien

Veröffentlicht

2012-08-14

Ausgabe

Bd. 2 Nr. 2 (2012)

Rubrik

Research Articles

Lizenz

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

·         I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.

·         I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).

·         I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.

·          I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

_______________

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.