Assessment of the Saliva and Serum Interleukine-6 in Patients with Chronic Periodontitis: Case Controlled Study
要旨
Abstract:Chronic periodontitis is a multifactorial disease characterized by an interaction between dental plaque antigen and components of the host defense system. Cytokines are considered to play a key role in the inflammation process in chronic periodontitis. The aim of the study was to assess the levels of Interleukin-6(IL-6) in saliva and serum of patients with chronic periodontitis and to compare them with the levels that observed in healthy subjects. This design of this study is case-controlled. The samples of study were collected from 30 subjects with chronic periodontitis and 30 healthy subjects that matched for age and sex, together. Salivary and serum IL-6, a marker of inflammation, was measured using enzyme–linked immunosorbent assay (ELISA) technology. The results showed a significant high serum and saliva levels of IL-6 in patients with chronic periodontitis as compared to healthy subjects were observed (P = 0.000). There was a statistically significant positive association (r = 0.36, p Ë‚ 0.05) between salivary IL-6 and the pocket depth in the chronic periodontitis. It concludes that in chronic periodontitis, systemic as well as the local levels of IL-6 as an inflammatory marker levels are increased indicating that chronic periodontitis is a systemic disease.Keywords: Chroinc periodontitis, saliva, serum, Interleukine-6Cite this article:Nankaly Haween T. Assessment of the saliva and serum interleukine-6 in patients with chronic periodontitis: Case controlled study. Research and Reviews: Journal of Microbiology and Virology. 2015; 5(1): 1–7p.
発行日
巻号
セクション
ライセンス
Declaration and Copyright Transfer Form
(to be completed by authors)
I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.
· I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.
· I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).
· I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.
· I/We also agree to the authorship of the article in the following order:
Author’s name
1. ________________
2. ________________
3. ________________
_______________
We Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal. |
