Isolation, Characterization of Rhinacanthus Nasutus L. Kurz and Its Biological Evaluation

Autor/innen

  • P. Jaya Preethi Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • K. Bindu Sree Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • A. Sirisha Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • Pavan Kumar Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • S. Ruby Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
  • T. Sivakumar Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India

Schlagwörter:

rhinacanthus nasuta (L) kurz, phytochemical screening, anti-inflammatory, analgesic, anti-bacterial.

Abstract

 The present paper deals with isolation, characterization and evaluation of anti-inflammatory, analgesic and anti-bacterial activities of n-hexane extract of Rhinacanthus nasutus L. Kurz. Extraction was carried out with soxhlet apparatus using solvents of increasing polarity. The anti-inflammatory activity was done by Carrageenan-Induced Paw Edema in rats. Analgesic activity was done by hot plate method and anti-bacterial activity by plate hole diffusion method. n-Hexane extract exhibited significant change in anti-inflammatory, analgesic activities when compared with the standard drug and control. Antibacterial screening of n-hexane extract was 100% active in concentration of 1000 µg/ml, 93% active in concentration of 500 µg/ml, and 87.5% active in concentration of 250 µg/ml.  

Autor/innen-Biografie

  • P. Jaya Preethi, Department of Pharmacy, Nandha College of Pharmacy and Research Institute, Koorapalayam Piruvu, Erode, Tamil Nadu, India
    pharmaceutical chemistry.

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Veröffentlicht

2013-04-22

Ausgabe

Bd. 3 Nr. 1 (2013)

Rubrik

Research Articles

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