A Possible Case of Methotrexate Induced Hepatic Cirrhosis

Auteurs-es

  • HARSHA R Clinical Pharmacology Unit, Department of Pharmacology
  • VIKRAM REDDY K Clinical Pharmacology Unit, Department of Pharmacology
  • MALATHESH UNDI DEPT OF COMMUNITY MEDICINE KIMS BANGALORE

Mots-clés :

methotrexate, psoriasis, cirrhosis

Résumé

A patient with psoriasis on long term methotrexate (MTX) therapy (cumulative dose=14.4 g) developed cirrhosis of liver associated with portal HTN and ascites. All the other possible causes for liver cirrhosis like HBV, HCV infection were ruled out. Investigations: antibodies (LKM-1), anti-mitochondrial antibodies (AMA 1,2,3,4,5,6,7,8,9), anti-treponemal antibody (TPHA), HBS Ag, anti-HCV were negative

Biographies de l'auteur-e

  • HARSHA R, Clinical Pharmacology Unit, Department of Pharmacology
    POST GRADUATEDEPT OF PHARMACOLOGY
  • VIKRAM REDDY K, Clinical Pharmacology Unit, Department of Pharmacology
    POST GRADUATEDEPT OF PHARMACOLOGY
  • MALATHESH UNDI, DEPT OF COMMUNITY MEDICINE KIMS BANGALORE
    POST GRADUATEDEPT OF COMMUNITY MEDICINE

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Publié

2013-04-22

Numéro

Vol. 3 No. 1 (2013)

Rubrique

Case Study

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