A Possible Case of Methotrexate Induced Hepatic Cirrhosis

著者

  • HARSHA R Clinical Pharmacology Unit, Department of Pharmacology
  • VIKRAM REDDY K Clinical Pharmacology Unit, Department of Pharmacology
  • MALATHESH UNDI DEPT OF COMMUNITY MEDICINE KIMS BANGALORE

キーワード:

methotrexate、 psoriasis、 cirrhosis

要旨

A patient with psoriasis on long term methotrexate (MTX) therapy (cumulative dose=14.4 g) developed cirrhosis of liver associated with portal HTN and ascites. All the other possible causes for liver cirrhosis like HBV, HCV infection were ruled out. Investigations: antibodies (LKM-1), anti-mitochondrial antibodies (AMA 1,2,3,4,5,6,7,8,9), anti-treponemal antibody (TPHA), HBS Ag, anti-HCV were negative

著者略歴

  • HARSHA R、 Clinical Pharmacology Unit, Department of Pharmacology
    POST GRADUATEDEPT OF PHARMACOLOGY
  • VIKRAM REDDY K、 Clinical Pharmacology Unit, Department of Pharmacology
    POST GRADUATEDEPT OF PHARMACOLOGY
  • MALATHESH UNDI、 DEPT OF COMMUNITY MEDICINE KIMS BANGALORE
    POST GRADUATEDEPT OF COMMUNITY MEDICINE

発行日

2013-04-22

巻号

セクション

Case Study