Evaluation of Anti-ulcer Activity of Ethanolic Extract of Salacia fruticosa and Oldenlandia Umbellata

Autoři

  • Saravanan Sampath The Erode College of Pharmacy, ERODE - 638112. Tamilnadu
  • Mohammed Ismail The Erode College of Pharmacy, ERODE - 638112. Tamilnadu
  • Manokaran Sellimuthu The Erode College of Pharmacy, ERODE - 638112. Tamilnadu

Klíčová slova:

Salacia fruticosa, Oldenlandia umbellate, anti-ulcer.

Abstrakt

In this present study the aerial and root parts of Salacia fruticosa and the entire herb of Oldenlandia umbellate were evaluated for its anti-ulcer property in Aspirin induced ulcer model and Pylorus ligation assays. Both plant materials were extracted with ethanol and given at the dose level of 200mg/kg orally after the LD50 studies to fix the dose. Ulcer index, free acidity and total acidity in pylorus ligated and aspirin induced ulcer models were calculated in Albino rats. Both of the plant extracts shows significant (P<0.01) anti-ulcer activity at the dose of 200 mg/kg.Keywords: Salacia fruticosa, Oldenlandia umbellate, anti-ulcer

Biografie autora

  • Saravanan Sampath, The Erode College of Pharmacy, ERODE - 638112. Tamilnadu
    Professor & Head,Dept. of Pharmaceutical Analysis

Stažení

Publikováno

2013-09-10

Číslo

Vol 4 No 2 (2013)

Sekce

Review Articles

Licence

Declaration and Copyright Transfer Form

(to be completed by authors)

I/ We, the undersigned author(s) of the submitted manuscript, hereby declare, that the above manuscript which is submitted for publication in the STM Journals(s), is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere.

·         I/We will not withdraw the manuscript after 1 week of submission as I have read the Author Guidelines and will adhere to the guidelines.

·         I/We Author(s ) have niether given nor will give this manuscript elsewhere for publishing after submitting in STM Journal(s).

·         I/ We have read the original version of the manuscript and am/ are responsible for the thought contents embodied in it. The work dealt in the manuscript is my/ our own, and my/ our individual contribution to this work is significant enough to qualify for authorship.

·          I/We also agree to the authorship of the article in the following order:

Author’s name                                    

 

1. ________________

2. ________________

3. ________________

_______________

We  Author(s) tick this box and would request you to consider it as our signature as we agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal.