A Brief Review of Interaction of Schiff Base Complexes with DNA: A Perceptive to Anti-cancer Agents

Auteurs-es

  • Rusal Raj Francis Birla Institute of Technology and Science, Pilani- Dubai campus
  • M. A. Neelakantan Chemistry Research Centre, National Engineering College, Kovilpatti, India

Mots-clés :

Schiff base complexes, DNA interaction, DNA binding, DNA cleavage

Résumé

Owing to the importance in design and development of new antitherapeutic and anticancer drugs, the contemporary research in this field requires an extensive study and untired contribution of bio-chemists in addition to that of pharmacologists and medical professionals. Keeping in view the recent reports in this field, especially, giving attention to the studies on the interaction of Schiff base complexes with DNA has been reviewed briefly. The recent trends in bio-inorganic chemistry field promises to fulfill the requirement of a variety of anticancer therapies. Qualitative results rather than quantitative were emphasized here as this would at least provide an insight into the recent developments in the field.

Biographie de l'auteur-e

  • Rusal Raj Francis, Birla Institute of Technology and Science, Pilani- Dubai campus
    Assistant Professor, Chemistry

Publié

2013-06-14

Numéro

Rubrique

Review Articles