Histopathological effects of silver nanoparticles on gills and liver of freshwater fingerlings Catla catla (Ham.)

Abstract

Fish is the best biomarker to identify the adverse effect on surroundings. Here, Fingerlings of major carp (Catla catla) were used as a model in the present work to investigate toxicity caused by silver nanoparticles (AgNPs). The fish exposed to different concentrations of 10 μg/L and 30 μg/L AgNPs for 15 days were sampled at days 5, 10 and 15 for histology. This exposure caused organ injuries, and the kinds of pathologies observed include aneurisms, necrosis in the secondary lamellae of the gills, clumping in cartilaginous core, congestion of secondary lamellae, and lifted up interlamellar epithelium. Liver histology exhibits various abnormalities including congestion of hepatocytes, pyknotic cells, severe hemorrhage and cellular clumping in central lobular vein, parenchymal vacuolization, focalnecrosis and dilation of sinusoid.

Keywords: AgNPs, Liver, Gill, Histopathology, Catla catla